![]() In a multicenter, open-label, randomized, parallel group study in 99 patients comparing the CANASA 1000 mg suppository administered nightly to that of the mesalamine 500 mg suppository twice daily. Table 1: Adverse Reactions Occurring in More Than 1% of Mesalamine Suppository Treated Patients (Comparison to Placebo) Symptom The most common adverse reactions in adult patients with mildly to moderately active ulcerative proctitis in double-blind, placebocontrolled trials are summarized in the Table 1 below. Nephrolithiasis īecause clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.Mesalamine-Induced Acute Intolerance Syndrome.The following serious or clinically significant adverse reactions are described elsewhere in labeling: Revised: Nov 2021 SLIDESHOW Inflammatory Bowel Disease (IBD) Causes, Symptoms, Treatment See Slideshow Keep away from direct heat, light or humidity.ĭistributed by: Allergan USA, Inc., Madison, NJ 07940. Store below 25☌ (77☏), may be refrigerated. Storage And HandlingĬANASA 1000 mg suppositories for rectal administration are available as bullet shaped, light tan to grey suppositories containing 1000 mg mesalamine supplied in boxes of 30 and 42 individually plastic wrapped suppositories ( NDC 58914-501-4-501-42). Keep CANASA away from these surfaces to prevent staining.ĬANASA Suppository: 1000 mg mesalamine in a bullet shaped, light tan to grey suppository. CANASA suppositories will cause staining of direct contact surfaces, including but not limited to fabrics, flooring, painted surfaces, marble, granite, vinyl, and enamel.Do not use two CANASA suppositories at the same time to make up for a missed dose. If a dose of CANASA is missed, administer as soon as possible, unless it is almost time for next dose.Retain the suppository for one to three hours or longer, if possible.Evaluate renal function prior to initiation of CANASA therapy.Safety and effectiveness of CANASA beyond 6 weeks have not been established. The recommended dosage of CANASAin adults is 1000 mg administered rectally once daily at bedtime for 3 to 6 weeks depending on symptoms and sigmoidoscopic findings. The structural formula is:ĬANASA is indicated in adults for the treatment of mildly to moderately active ulcerative proctitis. The empirical formula is C 7H 7NO 3, representing a molecular weight of 153.14. Each CANASA rectal suppository contains 1000 mg of mesalamine (USP) in a base of Hard Fat, NF. Chemically, mesalamine is 5-amino-2-hydroxybenzoic acid, and is classified as an anti-inflammatory drug. The active ingredient in CANASA 1000 mg suppositories for rectal use is mesalamine, also known as mesalazine or 5aminosalicylic acid (5-ASA). Tell your doctor if you have unlikely but serious side effects of Canasa including: Canasa is also used to prevent the symptoms of ulcerative colitis from recurring. Find Lowest Prices on What is Canasa and how is it used?Ĭanasa (mesalamine) is an anti-inflammatory drug used to treat ulcerative colitis, proctitis, and proctosigmoiditis. ![]()
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